PUK3 AN ECONOMIC MODEL OF OVERACTIVE BLADDER TREATMENT PERSISTENCE:TOLTERODINE ER COMPARED TO OXYBUTYNIN ER
نویسندگان
چکیده
منابع مشابه
Transdermal oxybutynin in the treatment of overactive bladder
Overactive bladder is a dreadful syndrome that affects a considerable number of patients. Antimuscarinics are the mainstay of pharmacotherapy for this condition. Transdermal (TD) oxybutynin (OXY) bypasses the first-pass metabolism and reduces the formation of N-desethyloxybutynin, a compound believed to be associated with anticholinergic side effects. The 3.9 mg matrix TD system is applied twic...
متن کاملOxybutynin topical gel in the treatment of overactive bladder
Overactive bladder (OAB), often accompanied by urinary incontinence, is most prevalent among the elderly, but also affects many middle-aged men and women in the US. OAB may severely impair quality of life, and its overall economic costs to society are substantial. Although antimuscarinic agents relieve OAB symptoms effectively, treatment persistence generally is low. This has been attributed in...
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HERD is a semi-algorithmic method for creating hierarchical ER diagrams from bottom up. The method is based on packaging operations that are applied in several steps on a given flat ER diagram. The result is a hierarchy of simple and interrelated diagrams (namely ER structures) with external relationships to other such diagrams. This chapter describes the application of HERD method using an exa...
متن کاملDevelopment of oxybutynin chloride topical gel for overactive bladder
Overactive bladder (OAB) is an age-related syndrome often associated with urinary incontinence. Symptoms of OAB, such as urgency, frequency, and nocturia, can be treated effectively with inhibitors of muscarinic acetylcholine receptors. Antimuscarinic agents promote relaxation of the detrusor muscle and may modulate afferent neuronal signals involved in the regulation of the micturition reflex....
متن کاملOxybutynin and Tolterodine in a Trial for Treatment of Overactive Bladder in Iranian Women
OBJECTIVE To evaluate the efficacy and side effects of Oxybutinin in comparison to tolterodine in treatment of overactive bladder (OAB) with detrussor overactivity (DOA) in Iranian women. MATERIALS AND METHODS One hundred Iranian old women with clinical symptoms of OAB who show IDO in the filling cystometry participated in this randomized double-blinded parallel-group by using two kinds of th...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2005
ISSN: 1098-3015
DOI: 10.1016/s1098-3015(10)63129-4